Profile of Eric Lander

Eric Lander and David Botstein on Mapping Quantitative Traits.

The rediscovery of Mendel’s work in the early 20th century sparked heated debate about the inheritance of continuously variable “size” traits (e.g., East 1916). But, although evidence accumulated in support ofMendelianmodels of quantitative trait inheritance, for most of the century it was rare for geneticists to be able to link such traits to specific Mendelian factors. The principles of mappi...

The CG Mars Lander

Design and Simulation of Lunar Soft Lander

In this paper, dynamic simulation and analysis for designing the soft landing of a lunar lander is focused. The primary objective of the lunar lander is to land safely on the surface of moon, without causing the lunar lander to topple and must attenuate the landing loads to preclude damage to the lander structure. The dynamic structural model of lunar lander is modelled and simulation described...

Breaking Lander-Waterman’s Coverage Bound

Lander-Waterman's coverage bound establishes the total number of reads required to cover the whole genome of size G bases. In fact, their bound is a direct consequence of the well-known solution to the coupon collector's problem which proves that for such genome, the total number of bases to be sequenced should be O(G ln G). Although the result leads to a tight bound, it is based on a tacit ass...

Eric Kandel